Liver metastases refer to the spread of cancerous cells from their primary site to the liver. This occurs when cancer cells break away from the original tumor and travel through the bloodstream or lymphatic system to establish new growth in the liver. Liver metastases are a common occurrence in advanced stage cancers such as colorectal, breast, lung, and pancreatic cancers. The presence of liver metastases often signifies advanced stage cancer and can significantly impact a patient's prognosis and treatment options. Treatment for liver metastases typically involves a combination of surgery, chemotherapy, radiation therapy, and targeted therapy. The goal of treatment is to control the spread of cancer, manage symptoms, and improve a patient's quality of life. Research in the area of liver metastases focuses on understanding the mechanisms underlying the spread of cancer cells to the liver, developing more effective treatments, and improving overall outcomes for patients with liver metastases. This research may involve studying the molecular pathways involved in metastasis, identifying new therapeutic targets, and evaluating the efficacy of novel treatment approaches. Overall, research in the area of liver metastases aims to advance our understanding of this complex disease and improve patient outcomes.